Men’s Health

Breaking news from the ACC:

Vytorin/Zetia gets panned - shows no benefit on the primary endpoint, though effective in reducing some markers. Doctors now wary and skeptical. Merck and Schering-Plough comment.  Good summary with more links from Ed Silverman (Pharmlot blog - one of the best btw!) here.
Prasugrel gets a boost - The investigational antiplatelet drug prasugrel plus aspirin produced a marked and highly statistically significant reduction in the risk of coronary stent thrombosis (ST) - a major concern for physicians and patients with potentially fatal consequences - in patients who received a stent as compared to standard therapy with clopidogrel (Plavix®) plus aspirin (1.13 percent vs. 2.35 percent, p<0.0001), according to a stent analysis from the head-to-head TRITON-TIMI 38 trial...more. And, more here from Pharmalot.

Angiomax: pretty much equivalent to heparin - A study released on Saturday found the two drugs worked about the same in low- to moderate-risk patients in preventing death, heart attack and the need to repeat medical intervention on a diseased blood vessel...more

Positive results for AstraZeneca's cholesterol-reducer Crestor - AstraZeneca Plc is stopping a clinical trial of its blockbuster cholesterol fighter Crestor early because of the clear benefits of the medicine compared to placebo, the company said on Monday...more

------OK, now on to other news:

Free drug samples - higher prescription costs? - Following free drug sample receipt, patients who receive these samples have significantly higher out-of-pocket prescription costs than those who don't, according to the first study to look at the out-of-pocket cost associated with free-sample use...more

Wyeth cutting 1,200 sales reps - The positions are being eliminated as of Monday as part of a major companywide program announced two months ago to save money in the face of regulatory setbacks and generic competition. At the time, the drugmaker acknowledged plans to cut about 10 percent of its global workforce of 50,000 or so, and that sales reps were high on the list. Wyeth employs roughly 25,000 people in the US...more

Sanofi-Aventis to give daily Cialis a boost - Sanofi-Aventis of France is partnering with Eli Lilly of America’s heartland to give Lilly’s impotence pill Cialis a boost over here...more

Speaking of Sanofi and Lilly: Lantus shows better efficacy than Humalog - A once-daily injection of Sanofi-Aventis's insulin drug Lantus controls blood sugar as effectively as Eli Lilly's Humalog, which needs to be taken three times daily, researchers said on Friday...more

Singulair trouble - suicide link? - The Food and Drug Administration said Thursday it is investigating a possible link between Merck's best-selling Singulair and suicide. FDA said it is reviewing a handful of reports involving mood changes, suicidal behavior and suicide in patients who have taken the popular allergy and asthma drug...more

Takeda drops cholesterol drug candidate lapaquistat - Takeda Pharmaceutical Co Ltd, Japan's biggest drug maker, on Friday dropped development of a cholesterol-lowering drug candidate that had once been seen as one of its most promising medicines...more

Otsuka pays for fraudulent Abilify marketing - Otsuka American Pharmaceutical, the US unit of the Japanese drugmaker, agreed to pay more than $4 million to resolve allegations that it marketed the Abilify antipsychotic for off-label uses...more

Disease-mongering brought to a whole new level (are these people serious)? - Anyone familiar with involuntary emotional expression disorder? This is another way of saying uncontrollable laughing or crying, and a little drugmaker called Avanir Pharmaceuticals hopes to market a pill for this “distinct neurological disorder.” Also known as pseudobulbar affect, the affliction has gotten talked up in recent years and investors are buying into the concept...more

The Vytorin studies - what will be revealed at the ACC meeting? Good news from the Enhance study? And why is the Improve-It study being expanded/delayed? Is it for sound data gathering reasons, or is it a conspiracy?

Physician gifting crackdown? - The latest legislative maneuver to control pharmaceutical marketing: Last week, congressman Pete Defazio (D-OR) introduced the Physician Payment Sunshine Act, a bill that will create a public registry of gifts and payments to physicians in excess of $25 by pharmaceutical companies...more

Lunesta moth flying away.

The other day I mentioned what I call the 'Mother Method' when deciding what products to market online. I got a couple of email from people wanting a bit more information, so here it is.

In short, the 'Mother Method' is my way of judging whether or not I think a product is worthy for me to market online. There is a lot of drive being sold out there today and I've found that if you want quality traffic, you need to be selling a quality product.

If I find a product that I think I may wat to market, I first buy it (as long as it has a 100% money-back guarantee so I can send it back if it's worthless), go through all the information in the ebook or course that I've just purchased and then once I've done all of that, I simply ask myself if I would recommend that product to my Mother.

Simply put, if a part of me says that no, I wouldn't, I just don't sell it. That little voice in your head is great for a few things, and helping you make decisions about whether or not to sell a product is one of them.

So next time you're in doubt about a product's quality, use the 'Mother Method' on it, works like a charm every time.

Robert. 

I spoke yesterday about some basic information on creating an online blog in order to promote your product through and today I'm going to go into depth about the kind of content that people will want to be reading about.

Let's say for example that you're promoting a health and fitness ebook, possibly one that's based around building muscle. Now if you're going to me marketing this product through a blog, you're going to want to write a personal review of sorts about the product in order to draw people in and hopefully get them to continue on and make a purchase.

When you begin writing, make sure you stay on topic - this is a huge point to remember. So many times I've seen people write what could have been the makings of a great article, however it usually ends up failing because they stray off topic too much.

Using the muscle-building ebook as an example, you'd want to stick with talking about how the product helped you build muscle and how easy you found the whole process. Straying off topic would be taking about how using a correct eating plan combined with this product will make the results even better.

Although it is related to the topic, by telling a potential customer this you're really not drilling the focus of the product itself into their mind. You only have a certain amount of time in which to convince someone to buy a product and if you're wasting valuable page space telling them things they really don't need to know in order to buy the product, the chance of them getting bored and leaving is increased greatly.

I'm not saying it's not good to include as much information as possible in order for your customer to make an informed decision, I'd just advise you to target the bare essentials in order to make your review as short and sweet as possible.

Take care all, good luck on your journey.

Robert.

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Drug Name

Cialis (Tadalafil)

Drug Uses

Cialis is used for treating erectile dysfunction in men (eg, impotence) and other conditions as determined by your doctor.

How Taken

Take Cialis exactly as your doctor prescribes. For most men, the recommended starting Cialis dose is 10 mg. It should be taken no more than once a day.

Drug Class and Mechanism

Cialis is a phosphodiesterase type 5 inhibitor and it works by helping the blood flow into the penis to achieve and maintain an erection during sexual stimulation.

Missed Dose

If you miss a dose of Cialis , take it as soon as you remember. Continue to use it as directed by your doctor.

Storage

Store Cialis at room temperature between 59 and 86 degrees F (15 and 30 degrees C).

Warnings/Precautions

Do not use Cialis if:

* you are allergic to any ingredient in Cialis;
* you have been told by your health care provider not to participate in sexual activity because of certain heart or health problems;
* you are taking or using any type of nitroglycerin (eg, under the tongue, capsule, tablet, spray, patch, ointment, paste) or other nitrates (eg, isosorbide), or recreational drugs ("poppers") containing amyl or butyl nitrate.

Contact your doctor or health care provider right away if any of these apply to you.

Possible Side Effects

The most common side effects with Cialis are headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects usually go away after a few hours.

Patients who get back pain and muscle aches usually get it 12 to 24 hours after taking Cialis. Back pain and muscle aches usually go away by themselves within 48 hours. Call your doctor if you get a side effect that bothers you or one that will not go away.
More Information

Sexual stimulation is required for Cialis to work. You will not get an erection just by taking Generic Cialis without sexual stimulation.

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One of the best ways to begin marketing affiliate products online is through the use of a blog. First of all it's a totally free resource that you can begin using in a matter of minutes and you can literally reach a global audience with them, so why not?

Once you have th affiliate product you intend to market (you do have one of those, don't you?), you then need to register for a blog. The two most utilised blogging softwares online are Blogger, which is owned by Google, and Wordpress. I prefer to use Wordpress myself, however if you're new to blogging I'd advise you stick with Blogger based on the fact that it's much easier to setup and use.

Obviously you'll need to base your blog around a topic that relates to the product you're selling. For example, if you're wanting to market a line of sexual health products like herbal aphrodisiacs or even erectile dysfunction medications like Viagra or Cialis, you would base your blog around sexual health.

When you begin writing, it's important to note you shouldn't make it sound like you're selling anything at all, merely sharing some information with others on the web who might be interested in it. Going with the sexual health theme again, you could write a story about how you were experiencing a lack in sexual energy when it came time to make love with your partner or spouse, but then you found a herbal remedy which helped you out a lot. You'd include your affiliate link somewhere in the article and hopefully someone would click on it and buy the product.

I've heard many people recommend that you should simply set up a single-post blog like a sales letter and just leave that there for people to find themselves. In my opinion this is not the best way to go about it as it usually appears more like a sales letter to a customer and not a genuine blog post, which then affects its credibility.

You want to set up your blog for long-term success and this means writing in it regularly in order to bring people back. Don't be scared in thinkin that it's something you need to work on every day in order to sustain some great traffic either. One of my blogs that I've only had up for arounf three months receives around 200 people per day in traffic and I only post once or twice a week on it.

Even if you're not an expert on whatever topic it is you want to be writing about, there are many ways you can gain information and knowledge to help you in writing your articles. Sites like Ezine Articles are fantastic as information resources and you can simple re-write what you read in your own words, effectively turning the article into your own work which can then be published on your blog.

Blogging is not something that will generally pay out for you in the short-term, but once you are generating some good traffic flow, will almost sustain itself.

So, hopefully you can use these pointers to make your next blogging-cum-affiliate-marketing venture not only fun, but very profitable! Take care and good luck!

University of California, San Francisco, CA, USA.
Erectile dysfunction is increasingly common with advancing age, yet sexual activity and intimacy are important to elderly men. AIM: To assess the efficacy and tolerability of tadalafil in men over the age of 65 years.
In this multicenter open-label study, 188 men (mean age = 71.6 years) who were over age 65 and did not have diabetes mellitus or clinical depression received Tadalafil 20 mg, taken on demand, for up to 12 weeks.
Efficacy was assessed using the International Index of Erectile Function (IIEF) and Sexual Encounter Profile (SEP). Psychosocial outcomes were evaluated using the Psychological and Interpersonal Relationship Scale (PAIRS).
Tadalafil treatment significantly improved all domains of the IIEF from baseline, including the erectile function (EF) domain (change = 8.8, end point = 21.6; P < 0.001). Mean per-patient percentage of "yes" responses to SEP questions concerning successful penetration (SEP2; change = 33.5%, end point = 73.5%; P < 0.001) and successful intercourse (SEP3; change = 39.6%, end point = 59.6%; P < 0.001) also improved significantly from baseline. Forty percent of the patients with baseline EF scores < 26 had normal EF (IIEF-EF domain scores > or = 26) at end point, and 81% reported improved erections in the Global Assessment Questionnaire. At least 56% of attempts at sexual intercourse were successfully completed (SEP3) at all time intervals up to 36 hours after Tadalafil administration. The patients also experienced significant improvement in both the sexual self-confidence and spontaneity domains of the PAIRS. Tadalafil was well tolerated, with < 5% of the patients discontinuing because of adverse events.
Tadalafil 20 mg was effective and well tolerated in elderly men with ED.

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Welcome.

In the vain hope that Perez Hilton or Hillary Clinton will mail and ask me to consult for them.

Failing that I'm ready for the deluge of junk mail I'm certain to receive; No doubt I'll be sold Viagra, Cialis and Levitra (of course I'd only consider Levitra having created the global PR campaign starring 'recently blogged' celebrity Jerry Hall)...

I'll probably be offered  images of all sorts of sexual positions (remember one man's deviant behaviour is another man's sexual sundae)... And no doubt Elliot Spitzer will drop me a note asking for a hooker.

Either way, it's nice to be contactable. I think. We'll see.

40% of men over the age of 40 suffer from impotence. Every men experiences some form of impotence once in his life. Changing lifestyles have also contributed to impotence in younger men. There is no exaggeration in saying that impotence is a very serious problem that can even grip you without any notice and ruin your life. The worst part about impotence is that it affects all aspects of men’s life.

Men consider any signs of erection problems as signs of weakness. This affects not only their sex life but also their personal and career life. Impotence has broken many marriages and ruined many relationships and until a decade ago, there was hardly any information available on this serious condition. People believed that impotence is a psychological problem that is bound to occur with age. However, one drug changed this thinking once and for all. This drug created something of a revolution and almost every adult around the world is aware of it. This dug is what we know as Viagra.

Viagra – A truly revolutionary drug

Viagra was the drug that changed people’s beliefs and made them realise that impotence is a physical condition which is more often than not caused by insufficient blood flow to the penis. Much before Viagra came online and people’s use of internet flourished, Viagra was popular by its own right. Today, millions of men buy Viagra UK online to treat their impotence and think of it nothing more than getting aspirin for headache. Even though many new drugs for impotence came up, the popularity of Viagra online and otherwise remains the highest.

Cialis – Budding competitor for Viagra

Many people who used to buy Viagra online before turned to Cialis online due to its 36 hours effectiveness. The popularity of Cialis UK online has definitely increased by leaps and bounds due to its higher efficacy but it still has not reached the level of Viagra. Now it remains to be seen, which of these drugs will rule the world in coming decade.